The showpiece event for the Bicentenary celebrations of the current Lord's Ground, MCC v Rest of the World, will take place on Saturday 5 July 2014.
The 50-overs-a-side match, which forms the centerpiece of a historic 2014 for the Home of Cricket, was announced as part of the ECB's full summer 2014 fixture list.
MCC Women's fixture against Rest of the World Women is the other major Bicentenary clash scheduled and will take place on Monday 19 May.
It will be the first time an MCC Women's side has played on the main Ground at Lord's and the first time ever a Women's Rest of the World Team has been assembled.
Teams for these historic matches will be announced at a later date, while tickets will become available as part of the 2014 major match ticket ballot which opens in December. To receive all the latest ticket information from Lord's, please register to recieve our emails.
MCC's other significant on-field celebrations take place from Friday 20 - Sunday 22 July, with the Bicentenary Festival Weekend.
In addition to the traditional fixtures between Oxford and Cambridge and Eton and Harrow, MCC take on Hertfordshire in a repeat of the first ever match at the current Lord's Ground, in 1814.
Middlesex CCC meanwhile will kick off the summer of cricket at Lord's when they take on Nottinghamshire in a LV= County Championship Division One clash starting on Sunday 13 April.
The Panthers, who are celebrating their 150th anniversary in 2014, play a total of fifteen fixtures at the Home of Cricket - including six LV=CC matches, four Royal London One Day Cup games and a one-day match against the touring Indians.
They play a further four matches in the revised NatWest t20 competition, including a first ever double-header, with Middlesex playing Sussex and Essex back-to-back on Saturday 17 May.
England's one ODI and two Tests at Lord's next year were announced near the end of the 2013 season.